上海交通大學(xué)生命科學(xué)技術(shù)學(xué)院于明課題組招聘博士后一名。應(yīng)聘人應(yīng)在近期獲得博士學(xué)位,熟悉分子生物學(xué)、動物細(xì)胞培養(yǎng)和小鼠遺傳學(xué)的基本操作。應(yīng)聘人在入職之后可以依照學(xué)校的政策逐級晉升。年薪不少于24.2萬;如果入選各級博士后激勵計劃、還會增加。其它待遇依照學(xué)校規(guī)定。本課題組的研究方向?yàn)檠?xì)胞發(fā)育和癌癥的轉(zhuǎn)錄調(diào)控,主要利用基因組學(xué)、蛋白組學(xué)、小鼠遺傳學(xué)和生物信息技術(shù)來闡明轉(zhuǎn)錄因子在生理?xiàng)l件下調(diào)控血細(xì)胞的發(fā)育的分子機(jī)理以及相關(guān)的轉(zhuǎn)錄失調(diào)誘發(fā)癌癥的分子機(jī)理。
聯(lián)系人:于明,郵箱:mingyu@sjtu.edu.cn(郵件標(biāo)題注明:應(yīng)聘崗位+畢業(yè)院校+本人姓名)
參考文獻(xiàn)
1. Yu, M., Yang, W., Ni, T., Tang, Z., Nakadai, T., Zhu, J., and Roeder, R.G. (2015) RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II. Science 350, 1383-1386.
2. Yu, M., Mazor, T., Huang, H., Huang, H. T., Kathrein, K. L., Woo, A. J., Chouinard, C. R., Labadorf, A., Akie, T. E., Moran, T. B., Xie, H., Zacharek, S., Taniuchi, I., Roeder, R. G., Kim, C. F., Zon, L. I., Fraenkel, E., and Cantor, A. B. (2012) Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors, Mol Cell 45, 330-343.
3. Yu, M., Riva, L., Xie, H., Schindler, Y., Moran, T. B., Cheng, Y., Yu, D., Hardison, R., Weiss, M. J., Orkin, S. H., Bernstein, B. E., Fraenkel, E., and Cantor, A. B. (2009) Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis, Mol Cell 36, 682-695.
4. Yu, M., Wan, M., Zhang, J., Wu, J., Khatri, R., and Chi, T. (2008) Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell development, Proc Natl Acad Sci U S A 105, 3873-3878.
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