Postdoctoral Research Scientist in Statistical Genomics of Hepatitis C

The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN

Grade 8: £37,382 – £44,607 with a discretionary range to £48,729 p.a.

Applications are invited for a postdoctoral research scientist to join the group of Dr Chris Spencer, to investigate the human genetics of infectious disease susceptibility. The role will require the creative development and application of new methods to large-scale genomics datasets. The post is an excellent opportunity for those with experience in statistical genetics, or individuals with a strong quantitative background, who wish to move into this exciting area.

You will play a key role in the STOP-HCV project, a recently funded MRC initiative to develop new tools to improve treatment of hepatitis C infection and to better understand the biology of related diseases. The project is collecting molecular data, including genotyping, sequencing, cellular phenotypes and biomarkers on a large patient cohort. Part of your role will be to help execute a large genomics experiment to assess and identify host genetic markers of treatment response. Using novel statistical methodology, our team will combine these data with whole-genome sequencing of the virus, in the same patients, to improve outcome prediction and to inform on key molecular interactions.

You will have a PhD with a strong quantitative component and experience of modern approaches to genetic analysis. You will need to be proficient in the use of statistical software, ideally R, and a low-level language. You should be able to work alone and collaboratively, and be able to digest and communicate scientific ideas effectively. You should enjoy visualising high-dimensional data, problem solving and drawing inferences from complex models.

This position is fixed term for 3 years in the first instance and is funded by the Medical Research Council.

Applications for this vacancy are to be made online. To apply for this role and for further details, including a job description and selection criteria, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=108841

Only applications received before 12:00, midday on Thursday 5th September 2013 can be considered.
You will be required to upload a CV and supporting statement as part of your online application, please quote reference 108841 in all correspondence.

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