Job Title: Post-doctoral Training Fellow: Biochemistry and Crystallography of the ubiquitin-proteasome system
Closing Date of vacancy: 11 October 2013
Division: Structural Biology
Team: Structural Electron Microscopy
Type of Contract: Fixed Term
Length of Contract: 3 years
Salary Range: £28,087 to £36,170 p.a. inclusive
Work Location: London
Hours per week: 35

The Institute of Cancer Research (ICR) is one of the world’s most influential cancer research institutes. Our mission is to make the discoveries that defeat cancer. We have a long and distinguished history of research with a major impact on the outcome for cancer patients. Our unique partnership with The Royal MarsdenNHS Foundation Trust (RMH) makes us the largest comprehensive cancer centre in Europe, performing high quality original basic research and translational studies. Under the leadership of Chief Executive Professor Alan Ashworth FRS, we are committed to attracting, developing and retaining the best minds in the world. The ICR was ranked as the UK’s top academic research centre in the 2008 Higher Education Funding Council Research Assessment Exercise. Based on our publication record, citations and impact we rank among the world’s leading cancer research centres.

We seek to appoint a Post-doctoral Training Fellow to Dr Edward Morris’ team in the Division of Structural Biology. The post is funded by a programme grant from Cancer Research UK. The successful applicant will undertake biochemical and crystallographic analysis of protein complexes associated with the ubiquitin-proteasome system, in particular the 26S proteasome and the COP-9 signalosome. The goal is to establish an improved understanding of these molecular machines which are either established or potential targets for cancer drugs.

Applicants should possess a PhD (or equivalent) in biological sciences. Experience in and enthusiasm for structural biology is essential and experience in protein biochemistry and protein crystallography is highly desirable.

Appointment will be on a Fixed Term Contract for 3 years in the first instance, with a starting salary in the range of £28,087 to £36,170 p.a. inclusive (based on previous post-doctoral experience).

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