The Department of Cancer Biology at University of Cincinnati has an opening for Postdoctoral Fellow to study transcriptional and epigenetic regulation of gene expression in breast cancer. The Zhang laboratory, located at the state-of-art Vontz Center for Molecular Studies, currently focuses on elucidating molecular mechanisms of gene- and tissue- specific transcriptional cofactors [Mol Cell 19:89-100, PNAS (2010) 107: 6765, PNAS (2010) 107:10196, JBC (2011) 286(20):17746, EMBO J. (2011) 30(12):2405, Cancer Research (2012) 72:5625] in breast cancer stem cell determination by using a combination of biochemical, molecular, genomic (RNA-seq, ChIP-seq) as well as mouse genetic (conditional knockout, mutant knockin and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors to overcome the endocrine and chemo- therapeutic resistance of human breast cancer.
Interested candidates must have a Ph.D. and/or M.D. degree with research experience in biochemistry, molecular or cellular biology. Prior experience with animal studies or RNA-seq/ChIP-seq is a plus. Salary is competitive with an attractive benefits package that includes generous family health insurance, retirement contributions, etc.
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