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時(shí)間:2015-08-12來源:博士人才網(wǎng) 作者:91boshi

Postdoctoral Position - Nogales Lab : Berkeley, CA, United States

Job Description

The Nogales lab, a Howard Hughes Medical Institute laboratory located at the University of California Berkeley, is seeking a highly creative, motivated, and skilled Postdoctoral Associate in the area of Structural Biophysics to study yeast septins assembly, interaction with lipids, and cellular ultrastructure. The successful candidate will apply his/her knowledge in membrane biophysics and cellular ultrastructure determination to unravel the mechanisms of septins cellular functions during cytokinesis involving their diffusion barrier and scaffolding roles.

 

Principal Responsibilities:

 

  • Expression and purification of septins for in vitro studies
  • Fluorescence studies of septin interaction with GUVs
  • Electron tomography studies of dividing yeast cells to characterize septin ultrastructure throughout the cell cycle

 

Preferred Qualifications:

 

  • Strong background and publication record in membrane biophysics and/or cellular ultrastructure characterization
  • Experience with membrane interacting proteins, GUVs and/or quantitative fluorescence microscopy
  • Experience with cellular electron microscopy (embedding and sectioning) and tomography, and/or general biochemistry/molecular biology techniques.

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