Cold Spring Harbor Laboratory Cold Spring Harbor, New YorkBased on Level of Experience

The Sheltzer Lab at Cold Spring Harbor Laboratory is seeking candidates for an NIH-funded postdoctoral position in cancer genetics and cell biology.

The Sheltzer Lab is combining functional genomics, molecular biology, and bioinformatics to study the consequences of copy number alterations (aneuploidy) in human tumors. Currently, we are developing novel systems to model aneuploidy in vitro and in vivo to expand our ability to investigate how genomic imbalances influence cell physiology. We are particularly interested in determining the role that aneuploidy plays in cancer evolution, and in identifying therapeutic vulnerabilities created by the aneuploid cell state.

This work will build upon our prior research, including our discovery that certain aneuploidies function as tumor suppressors (DOI: 10.1101/040162), the demonstration of a novel link between aneuploidy and genome instability (PMID: 21852501), and the elucidation of transcriptional patterns caused by aneuploidy in primary and transformed cells (PMID: 22802626 and 24041940). More information on research in the Sheltzer Lab can be found at http://sheltzerlab.labsites.cshl.edu/.

Cold Spring Harbor Laboratory is located on Long Island, outside of New York City, in New York, USA. Home to eight Nobel Laureates, Cold Spring Harbor provides an immersive and highly-collaborative research environment on the shores of the Long Island Sound. Cold Spring Harbor is an NCI-designated Cancer Center, and every year, over 10,000 scientists journey to Cold Spring Harbor to attend one of CSHL’s famous Meetings and Courses.

Candidates for this position should have a Ph.D. in Molecular Biology, Biochemistry, Cell Biology, or a related field. Questions about the position can be addressed to Dr. Sheltzer at sheltzer@cshl.edu.

Interested candidates should also apply via the CSHL Careers website at: https://cshl.peopleadmin.com/postings/9796

Position number 01430-R

CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status.

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