Postdoctoral Scientist - Heart Institute : Los Angeles, CA, United States

Postdoctoral Scientist – Heart Institute
Los Angeles, CA
Cedars-Sinai

A Posdoctoral research position is available in the laboratory of Joshua I. Goldhaber, M.D. Director of Basic Research Programs, in the Heart Institute at Cedars-Sinai Medical Center in Los Angeles, CA. The Goldhaber laboratory studies the role of intracellular calcium cycling in cardiac pacemaking and excitation-contraction coupling in health and disease models, with a particular focus on the sodium-calcium exchanger and voltage-sensitive calcium channels. The lab employs a variety of techniques including single cell patch clamp electrophysiology, high resolution voltage and calcium mapping, fluorescence photometry, laser scanning confocal, TIRF, super resolution and multiphoton microscopy, mouse MRI, cardiac cell isolation, and various molecular techniques. The vibrant basic and translational research program in the Heart Institute at Cedars-Sinai, in addition to our existing relationships with UCLA, provides excellent opportunities for career development in cardiac research and mentoring for post-doctoral researchers.

Our studies require isolation of cardiomyocytes (ventricular, atrial, or sinoatrial node cells) or whole sinus node and atrial tissue sheets from either mice, rats or rabbits, patch clamping technique to study various ion currents, extensive use of a state of the art laser scanning confocal microscope to study subcellular calcium and other ion characteristics in live myocytes, immunostaining in fixed tissue, qPCR, western blotting, analysis and interpretation of data, preparing manuscripts and posters, presenting slide presentations at national meetings, and applying for fellowships and grants.

Required Qualifications: This candidate must have a M.D. or Ph.D. in biophysics, biochemistry, physiology, molecular biology, or related field and demonstrate hands-on experience with voltage/calcium imaging or patch clamping in cardiac cells. Additional experience in molecular biology, cell culture techniques and animal handling is a plus. Candidates must possess good command of both written and spoken English and are expected to write applications for extramural funding. Applicants should have good organizational skills, and interact/collaborate well with other lab members.

In addition to professional development opportunities, Cedars-Sinai offers a competitive compensation and benefits package.

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