The position

　　The Department of Human Genetics at the LUMC has an NWO-funded postdoctoral position available in the group of Lucia Daxinger to investigate epigenetic regulation in health and disease..

　　You will be part of an international research group investigating the molecular function of a set of factors involved in DNA methylation and histone modification pathways that have been directly linked to human disease. Using knock down, conventional and CRISPR-based knock in/knock out approaches, we employ unbiased genome-wide methods (RNA-seq, ChIP-seq, WGBS, ATAC-seq) to expose transcriptomic and epigenomic dysregulation in a range of mammalian model systems. In complementary mechanistic/biochemistry studies we are characterizing how our factors of interest interact with other members of the epigenetic machinery and contribute to regulate gene expression patterns.

　　The profile

　　You are an enthusiastic and driven individual who:

　　·         holds a recent PhD in Genetics, Molecular Biology or a related field;

　　·         has a strong background in epigenetics;

　　·         has a demonstrated publication record;

　　·         is experienced with stem cell culture and analysis, interpretation and integration of next generation sequencing data (major plus)

　　·         possesses excellent written and oral communication skills in English.

　　Our offer

　　Appointment is for 36 hours per week. You will be appointed for one year, with a possible extension for two years. You salary is based on your education and experience and is a maximum of € 4,216 gross per month based on fulltime employment (scale 10 of the Collective Labor Agreement UMC).

　　Working at the LUMC

　　The Department of Human Genetics is a broadly oriented research department with focus on the (epi)genomic contribution to inherited and acquired diseases. The Department consists of twenty self-contained research groups that perform research in four different themes. This project fits within the theme 'Molecular Technology and Informatics for Personalised Medicine and Health'. This theme is embedded in the LUMC Medical Research Profile 'Translational Neurosciences'.

　　More information

　　The complete vacancy can be found on www.lumc.nl/vacatures. You can also contact Dr Lucia Daxinger, Group leader, Department of Human Genetics, +31(0)71 526 94 48.

　　For this position, a letter of motivation describing your interest in the research area, a curriculum vitae, and the contact details of at least two references are requested. The application procedure will include one or more interviews. In addition, candidates may be asked to give a presentation.

　　Applying

　　If you want to apply, make sure to fill in our application form before the 11th of November 2018. You can also apply directly via www.lumc.nl/vacatures.

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