Fixed-term: The funds for this post are available for 1 year in the first instance.

　　Applications are invited for a post-doctoral research associate to work with Professor Christopher Hunter in the Department of Chemistry at the University of Cambridge to work on an EPSRC programme to develop artificial transmembrane signaling systems. The appointee will join a multidisciplinary team of several post-docs and PhD students based in Cambridge combining expertise in supramolecular chemistry, organic synthesis, polymer chemistry and computational chemistry.

　　The aim is to develop molecular systems which are capable of transmitting chemical information across a lipid membrane in a similar manner to coupled membrane protein receptors.  Transduction of a chemical signal from the outside of a vesicle is to be achieved via controlled translocation which will trigger a chemical process on the inside of the vesicle.  Relatively simple building blocks will be used so that a range of different strategies can be explored.  The appointee will work as part of a larger team in collaboration with the research group of Professor Nick Williams (University of Sheffield). The role will involve organic synthesis of the building blocks equipped with appropriate recognition sites; studies of the binding properties of these systems; incorporation into vesicles; assessment of recognition triggered transmembrane signalling properties. The Sheffield group will explore different chemical processes that can be triggered on the inside of the vesicles.

　　Applicants should have (or be about to obtain) a PhD in chemistry. Experience in some or all of organic synthesis, supramolecular chemistry and membrane chemistry is required. The appointees will be expected to give oral presentations on their work, write internal reports and produce draft publications, and relevant communication skills are required. In addition to their own research, the appointees will be expected to take some responsibility for the supervision and training of post-graduate and undergraduate research students and for the day-to-day running of the laboratory.

　　To apply online for this vacancy and to view further information about the role, please visit:

　　http://www.jobs.cam.ac.uk/job/19084. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

　　Please ensure that you upload your Curriculum Vitae (CV), a covering letter and publications list in the upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

　　For queries regarding applying online for these posts, please contact Dr M Cristina Misuraca (e-mail: herchelsmith.orgchem@ch.cam.ac.uk).

　　Please quote reference MA16986 on your application and in any correspondence about this vacancy.

　　The University values diversity and is committed to equality of opportunity.

　　The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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