招聘簡介:

　　傳染病疫苗研究和宿主-病原體相互作用的博士后職位

　　·新墨西哥大學(xué)

　　·地點：新墨西哥州阿爾伯克基

　　·工作編號：7056527

　　·發(fā)布日期：2019年3月19日

　　·申請截止日期：2019年4月21日

　　職位描述

　　傳染病疫苗研究和宿主-病原體相互作用的博士后職位

　　美國國立衛(wèi)生研究院資助的新博士后職位可在新墨西哥大學(xué)藥學(xué)學(xué)院藥物科學(xué)系副教授Pamela Hall的實驗室獲得�；魻枌嶒炇椅挥谛履�西哥州阿爾伯克基市新墨西哥大學(xué)健康科學(xué)中心校園的多學(xué)科研究設(shè)施內(nèi)。

　　研究：我們研究宿主對金黃色葡萄球菌感染的天然防御和抑制毒力的疫苗干預(yù)。候選人將結(jié)合免疫學(xué)、分子生物學(xué)和微生物學(xué)方法，評估基于病毒樣顆粒（VLP）的疫苗策略控制金黃色葡萄球菌毒力因子生產(chǎn)的臨床前潛力（Daly等人，2017年，科學(xué)報告，doi:10.1038/s41598-017-00753-0）。NIAID/NIH的R01目前支持這項工作。除了評估金黃色葡萄球菌感染的多種模型（包括免疫功能降低模型）的疫苗功效外，候選人還將設(shè)計和生產(chǎn)新型的基于VLP的疫苗。職責(zé)包括獨立研究、交流研究結(jié)果、參加當(dāng)?shù)仄诳�社和進行中的工作報告。

　　英文原文：

　　Post-Doctoral Position in Infectious Disease Vaccine Research and Host-Pathogen Interaction

　　·         University of New Mexico

　　·         Location: Albuquerque, NM

　　·         Job Number: 7056527

　　·         Posting Date: Mar 19, 2019

　　·         Application Deadline: Apr 21, 2019

　　Job Description

　　Post-Doctoral Position in Infectious Disease Vaccine Research and Host-Pathogen Interaction

　　A new NIH-funded postdoctoral position is available in the laboratory of Pamela Hall, Ph.D., Associate Professor in the Department of Pharmaceutical Sciences at the University of New Mexico College of Pharmacy. The Hall laboratory is located in the Multidisciplinary Research Facility on the University of New Mexico Health Sciences Center campus in Albuquerque, NM.

　　Research: We study host innate defense against Staphylococcus aureus infection and vaccine interventions to inhibit virulence. The candidate will combine immunology, molecular biology, and microbiological approaches to evaluate the preclinical potential of a virus-like particle (VLP) based vaccine strategy to control production of S. aureus virulence factors (Daly et al, 2017, Scientific Reports, doi: 10.1038/s41598-017-00753-0). This work is currently supported by an R01 from NIAID/NIH. In addition to evaluating vaccine efficacy in multiple models of S. aureus infection, including models of reduced immune function, the candidate will design and produce novel VLP-based vaccines. Responsibilities include independent research, communication of research results, and participation in local journal clubs and Works-in-Progress presentations.

　　Qualifications: At a minimum, the successful candidate must have a Ph.D. in Molecular Biology, Immunology, Microbiology, Biochemistry or a related field with a record of peer-reviewed publications. The ideal applicant should have extensive experience in molecular cloning, protein expression and purification (FPLC), and mouse models of disease. Candidates with experience in in vivo imaging and vaccine research will be given preference. Experience in immunology, especially complex flow cytometry studies, is a plus. The ideal candidate should be highly motivated with demonstrated ability to carry out independent research.

　　Instructions: Applications should include a cover letter describing the goals of the candidate for postdoctoral training, curriculum vitae, including a list of peer-reviewed publications, a brief description of current/prior research activities, and the contact information for three references. Interested applicants should submit materials to Dr. Pamela Hall by email at phall@salud.unm.edu. For best consideration, please apply on or before May 1, 2019. Proof of Authorization to Work in the U.S. is a precondition of employment.

　　UNM's confidentiality policy ("Recruitment and Hiring," Policy #3210), which includes information about public disclosure of documents submitted by applicants, is located at http://policy.unm.edu/university-policies/3000/3210.html. The University of New Mexico is an Equal Opportunity/Affirmative Action employer and educator.

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