招聘簡介：

　　關于團隊/工作

　　Boulard和Gross團隊正在尋找一位對表觀基因組學和轉錄組學有濃厚興趣的生物信息學博士后研究員，以領導對表觀遺傳學和神經(jīng)科學接口項目框架中生成的大規(guī)模“OMIC”數(shù)據(jù)集的分析。

　　本項目結合了Boulard和Gross兩組在染色質生物學和神經(jīng)回路方面的專業(yè)知識，分別探索轉錄因子和大腦表觀基因組之間的細胞類型特異性相互作用。成功的申請者將加入一個由分子生物學家、生物化學家和神經(jīng)科學家組成的合作團隊。

　　你的角色

　　指定人員將負責大規(guī)模表觀基因組和轉錄組數(shù)據(jù)集的計算分析，包括：

　　1）開發(fā)分析Cutnrun和DAP Seq數(shù)據(jù)集的方法和管道，以及

　　2）集成、比較、挖掘和可視化“OMIC”數(shù)據(jù)集。

　　該職位涉及與濕實驗室科學家合作開發(fā)和實施定制分析。

　　英文原文：

　　About the team/job

　　The Boulard and Gross Groups are seeking to recruit a Postdoctoral Fellow in bioinformatics with a strong interest in epigenomics and transcriptomics to lead the analysis of large-scale “omic” datasets generated in the frame of a project at the interface of epigenetics and neuroscience.

　　This project combines the expertise of the Boulard and Gross groups in chromatin biology and neural circuits, respectively, to explore the cell-type specific interplay between transcription factors and the brain epigenome. The successful applicant will be embedded in a collaborative team of molecular biologists, biochemists, and neuroscientists.

　　Your role

　　The person appointed will be responsible for the computational analyses of large-scale epigenomic and transcriptomic datasets, including:

　　1) developing methods and pipelines to analyze CutnRun and DAP-seq data sets, and

　　2) integrating, comparing, mining, and visualizing “omic” data sets.

　　The position involves the development and the implementation of custom analyses in collaboration with wet-lab scientists.

　　You have

　　·         PhD degree in Bioinformatics, Computer Science, Mathematics, or related fields.

　　·         Solid skillset and experience in bioinformatics:

　　o    Excellent knowledge of R and biostatistics

　　o    Experience and proven track record in handling NGS datasets and developing analysis pipelines

　　·         Outstanding interpersonal and communication skills are essential

　　You might also have

　　·         Experience with Unix-based environment and high-performance computing cluster environment is not required, but would be considered an advantage.

　　·         Experience in motif discovery is not required, but would be considered an advantage.

　　Why join us

　　The European Molecular Biology Laboratory (EMBL) is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits. Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

　　What else do I need to know

　　EMBL is one of the highest ranked scientific research organizations in the world. We are an international, innovative and interdisciplinary laboratory with more than 1600 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton, Hamburg, Grenoble and Rome. The Neurobiology and Epigenetics Unit at EMBL Rome studies mammalian physiology from the molecular to the systems level using the laboratory mouse as a model system. We take advantage of a full range of core facilities, including bioinformatics services and a high-performance computing cluster.

　　For more information, please see our website at www.embl.it.

　　To apply please submit a cover letter clearly stating your motivation and future research interests/plans and a CV with at least two referees through our online system at www.embl.it/jobs.

　　Applications are welcome from all nationalities, appointment will be based on merit alone.

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