招聘簡介：

　　精密疫苗實驗室由Ofer Levy MD博士指導(dǎo)，是波士頓兒童醫(yī)院/哈佛醫(yī)學(xué)院（波士頓，馬薩諸塞州，美國）精密疫苗項目的焦點。由于不同的免疫力，危及生命的感染最常發(fā)生在極端的生命中，促使開發(fā)出在年輕人和老年人中安全有效的改良疫苗。精準(zhǔn)疫苗計劃是一個國際合作平臺，采用尖端技術(shù)了解免疫反應(yīng)的年齡和性別特征，為開發(fā)針對不同人群的最佳安全性和免疫原性的疫苗開發(fā)提供信息。我們尋找一位技術(shù)嫻熟，有動力的博士后科學(xué)家，具有免疫學(xué)背景（T和B淋巴細(xì)胞研究經(jīng)驗），疫苗學(xué)和/或系統(tǒng)生物學(xué)，領(lǐng)導(dǎo)一個新型佐劑疫苗開發(fā)項目。

　　英文原文：

　　The Precision Vaccines Laboratory, directed by Ofer Levy MD, PhD, is the focal point of the Precision Vaccines Program at Boston Children’s Hospital/Harvard Medical School (Boston, MA; USA). Due to distinct immunity, life-threatening infections most often occur at the extremes of life motivating development of improved vaccines that are safe and effective in the young and old. The Precision Vaccines Program is a platform for international collaboration employing cutting edge technologies to understand age- and sex-specific features of immune responses to inform development of vaccines tailored for optimal safety and immunogenicity towards distinct populations. We seek a skilled and motivated post-doctoral scientist with background in Immunology (experience in T and B lymphocyte studies a plus), Vaccinology, and/or Systems Biology to lead a project on development of novel adjuvanted vaccines. We are funded by NIH/NIAID via an Adjuvant Discovery and Development Program contracts, a UO1 grant on adjuvant synergy and a U19 Human Immunology Project Consortium (HIPC) award to study systems vaccinology. Studies will employ in vitro modeling of human newborn, adult and elderly antigen-presenting cells, T and B lymphocytes, small molecule screens, medicinal chemistry, adjuvant formulation as well as in vivo animal and human studies and big data “OMIC” technologies, to identify and develop adjuvants that enhance immune responses of those at the extremes of age. Our laboratory is dynamic, international, supportive and productive. We offer excellent opportunities for publication, attendance at scientific meetings, and career advancement with graduates of the lab holding prominent positions in academia and industry. The candidate should have obtained their PhD within the last 1-3 years. Interested applicants should e-mail their CV and arrange to have 3 statements of reference e-mailedto: ofer.levy@childrens.harvard.edu. International candidates are encouraged to apply.

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