招聘簡介：

　　位置：

　　博士后位置在A是可用的encalada在斯克里普斯研究所的實驗室在美國加州拉荷亞區(qū)，在神經(jīng)退行性疾病，衰老，和intracellular運輸。我們的實驗室是有興趣的分子調控機制characterizing學院電機驅動運輸?shù)纳窠?jīng)元，在神經(jīng)退行性病變的作用，運輸和缺陷與衰老和機制，錯誤折疊的蛋白質，參與學院學院傳播的朊病毒疾病，阿爾茨海默氏病，甲狀腺素運載蛋白變性和tau蛋白病。我們調查的機制所形成的液－液相分離在神經(jīng)退行性疾病，包括神經(jīng)，我們生成的模型中的各種疾病。你將有機會做研究的知識背景在斯克里普斯研究A，由A的組合的應用細胞生物學，遺傳學，生物化學，和高分辨率的定量光顯微鏡和EM的研究在不同的模型系統(tǒng)，包括哺乳動物和線蟲的神經(jīng)元，小鼠。

　　在斯克里普斯研究所坐落在美麗的加州拉荷亞，是一個世界上最大的，私人的，非盈利組織，研究狀態(tài)的基礎和Forefront在生物醫(yī)學科學的翻譯后修飾。所提供的世界一流的資源和環(huán)境，促進合作，協(xié)同制造，榮獲優(yōu)秀發(fā)現(xiàn)這里。

　　英文原文：

　　POSITION:

　　A postdoctoral position is available in the Encalada Laboratory at The Scripps Research Institute in La Jolla, California, USA, in the areas of neurodegeneration, aging, and intracellular transport. Our lab is interested in characterizing the mechanisms of regulation of molecular motor-driven transport in neurons, the role that defective transport plays in neurodegeneration and aging, and the mechanisms of spreading of misfolded proteins involved in prion diseases, Alzheimer’s disease, transthyretin amyloidoses, and tauopathies. We also investigate the mechanisms of formation of liquid-liquid phase separations in neurodegeneration including in neuronal models that we have generated for various diseases. You will have the opportunity to do research in a superb intellectual setting at Scripps Research, by applying a combination of cell biology, genetics, biochemistry, and high-resolution quantitative light and EM microscopy to your research in various model systems including mammalian neurons, mice, and C. elegans.

　　The Scripps Research Institute is located in beautiful La Jolla, California, and is one of the world’s largest, private, non-profit research organizations that stands at the forefront of basic biomedical and translational science. The institute provides world-class resources and a cooperative, collaborative environment, which promotes the outstanding discoveries made here.

　　REQUIREMENTS:

　　1.    You are about to complete your PhD or have completed your PhD within the last year in cell biology, genetics, neurobiology, molecular biology, biophysics, or related field.

　　2.    Highly motivated, independent, with outstanding written and oral communication skills, and with peer-reviewed publications.

　　3.    Research experience with cell biology and light or super-resolution microscopy is highly desirable.

　　Interested candidates please send a CV with a list of publications, a brief statement of your previous research expertise, your postdoctoral research interests, and the contact information of three referees to Sandra Encalada atencalada@scripps.edu. For more information also please consult our website at http://www.scripps.edu/encalada/encalada/HOME.html

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