招聘簡介:
與唇裂和腭裂風(fēng)險(xiǎn)相關(guān)的基因調(diào)控網(wǎng)絡(luò)
康奈爾集團(tuán)正在研究與口腔劈裂風(fēng)險(xiǎn)增加相關(guān)的常見和罕見遺傳變異的病理機(jī)制。目前的項(xiàng)目主要集中在控制周皮和神經(jīng)嵴分化的基因調(diào)控網(wǎng)絡(luò)上。切割和運(yùn)行,ATAC-seq,nNanostring分析,基因組工程和體內(nèi)報(bào)告分析都為此目的而部署。
英文原文:
Gene regulatory networks relevant to risk for cleft lip and palate
The Cornell group is investigating pathological mechanisms underlying common and rare genetic variants associated with increased risk for orofacial clefting. Current projects focus on gene regulatory network governing differentiation of periderm and neural crest. Cut-and-run, ATAC-seq, nNanostring profiling, genome engineering, and in vivo reporter assays are all deployed to this end. A partial list of publications from the Cornell group is found here/
https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40335873/?sort=date&direction=descending
Candidates must have a PhD in a related scientific discipline and at least one first author publication. A background in developmental biology, cell biology or genetics is preferred. Experience in bioinformatics is desirable. Interested candidates should submit their Curriculum Vitae, a cover letter, and complete contact information for two or three references to the Jobs@UIOWA online application below.
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