招聘簡介：

　　在舊金山加利福尼亞大學(xué)Nakamura實驗室，鼓勵有興趣研究腫瘤轉(zhuǎn)化分子機制的翻譯重點。Jean Nakamura博士，首席研究員，是癌癥中心的內(nèi)科醫(yī)生和執(zhí)業(yè)腫瘤學(xué)家。中村研究計劃的一個核心目標是為腫瘤領(lǐng)域的應(yīng)用開發(fā)創(chuàng)新的診斷和治療策略，為此，實驗室在基因組學(xué)、代謝、臨床前實驗和成像領(lǐng)域與多個跨學(xué)科、翻譯研究小組合作。

　　我們的實驗室位于加州大學(xué)舊金山分校MissionBay校區(qū)的Helen Diller家庭癌癥研究大樓。作為UCSF最新的校區(qū)，Mission Bay校區(qū)是一個充滿活力、科學(xué)活力的環(huán)境，擁有眾多共享資源，支持前沿研究。在這個高度協(xié)作、多學(xué)科的環(huán)境中，我們對小鼠和人類腫瘤進行了整合的基因組和功能分析，以研究致癌的分子機制。該實驗室在研究不同惡性腫瘤的信號轉(zhuǎn)導(dǎo)通路作為治療靶點和建立小鼠體內(nèi)腫瘤發(fā)生模型方面具有特殊的專長。合適的候選人是將獲得或最近獲得博士學(xué)位的個人。我們研究體外和體內(nèi)模型以及原發(fā)性人類癌癥標本，主要目的是將我們的研究結(jié)果轉(zhuǎn)化為治療和預(yù)防的研究試驗。

　　英文原文：

　　Individuals interested in investigating the molecular mechanisms of tumorigenesis with a translational emphasis are encouraged to apply for postdoctoral training in the Nakamura laboratory at the University of California San Francisco. Dr. Jean Nakamura, the Principal Investigator, is a physician-scientist and a practicing oncologist in the Cancer Center. A core objective of the Nakamura research program is to develop innovative diagnostic and therapeutic strategies for applications in oncology, and to this end, the lab collaborates with multiple interdisciplinary, translational research groups in the areas of genomics, metabolism, pre-clinical experimentation and imaging.

　　Our laboratory is located in the Helen Diller Family Cancer Research Building at the Mission Bay Campus of UCSF. The newest of the UCSF campuses, the Mission Bay campus is a dynamic, scientifically vibrant environment with numerous shared resources to support cutting-edge research. In this highly collaborative, multidisciplinary environment, we have integrated genomic and functional analysis of mouse and human tumors to investigate molecular mechanisms driving cancer. The lab has particular expertise in studying signal transduction pathways in diverse malignancies as therapeutic targets and developing mouse models of in vivo tumorigenesis. Appropriate candidates are individuals who will be awarded or recently awarded PhDs. We study in vitro and in vivo models as well as primary human cancer specimens and a major goal is to translate our findings into investigational trials for both therapeutics and prevention.

　　The postdoctoral fellow will be expected to develop a leadership role in a project and contribute as a collaborator to other efforts. Areas of study in our laboratory include cancer metabolism, kinase signaling, response to ionizing radiation and mechanisms of cancer resistance to therapy. Individuals having research experience in cell biology, biochemistry, kinase signaling, cellular metabolism and/or use of mammalian model organisms are sought. The postdoctoral fellow will have the opportunity to be involved in highly collaborative research involving multiple research groups (clinical and basic science) within UCSF as well as nationally and internationally. Strong communication skills (written and verbal) in English are mandatory.

　　Career development opportunities include development of scientific presentation and writing skills, development of leadership role in collaborative research, as well as paper presentation at national and international meetings. A PhD and fluency in spoken and written English are required.

　　Send curriculum vitae and contact information for three references to Jean Nakamura, M.D., Department of Radiation Oncology, University of California, San Francisco, 1450 Third Street, Room 266, San Francisco, CA 94158. Email: Jean.nakamura@ucsf.edu. UCSF is an equal opportunity employer.

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