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瑞士洛桑理工學(xué)院先天免疫實(shí)驗(yàn)室博士后招聘

時(shí)間:2019-05-10來(lái)源:中國(guó)博士人才網(wǎng) 作者:佚名

 招聘簡(jiǎn)介:

  由Andrea Ablasser領(lǐng)導(dǎo)的洛桑理工學(xué)院(EPFL)先天免疫實(shí)驗(yàn)室邀請(qǐng)申請(qǐng)博士后職位。

  “細(xì)胞內(nèi)先天免疫”

  DNA具有高度免疫原性。微生物DNA是宿主先天免疫系統(tǒng)檢測(cè)到的關(guān)鍵病原相關(guān)分子模式。同樣地,宿主dnacan也會(huì)引發(fā)有效的先天免疫反應(yīng),一方面支持抗腫瘤免疫,另一方面也會(huì)引發(fā)有害的炎癥或自身免疫反應(yīng)。我們的研究旨在在分子水平上描述先天性DNA傳感機(jī)制的調(diào)節(jié)機(jī)制,最終目的是為炎癥性疾病的治療干預(yù)制定新的策略。

  博士后職位的申請(qǐng)人應(yīng)持有生物科學(xué)(生物)化學(xué)或相關(guān)學(xué)科背景的生命科學(xué)博士學(xué)位,并應(yīng)在同行評(píng)審的期刊上有良好的出版記錄。我們正在尋找對(duì)科學(xué)和研究充滿熱情、有才華、有創(chuàng)造力和熱情的候選人。

  我們的實(shí)驗(yàn)室是一個(gè)高度協(xié)作的環(huán)境,重視嚴(yán)格的研究。它位于瑞士?jī)伤?lián)邦理工學(xué)院之一的EPFL主校區(qū),日內(nèi)瓦湖沿岸,阿爾卑斯山腳下。

  英文原文:

  The Laboratory of Innate Immunology headed by Andrea Ablasser at the École Polytechnique Fédérale de Lausanne (EPFL) invites application for a Postdoc Position on

  “Intracellular innate immunity

  DNA is highly immunogenic. Microbial DNA serves as a key pathogen-associated molecular pattern detected by the host innate immune system. Likewise, host DNAcan also trigger potent innate immune response that one the one hand supports antitumor immunity, but on the other hand also fuels deleterious inflammatory or autoimmune reactions. Our research aims to describe at the molecular level the mechanisms underlying the regulation of innate DNA sensing mechanisms with the ultimate goal to define new strategies for therapeutic interventions into inflammatory diseases.

  Applicants for the Postdoc position should hold a Ph.D. in life sciences with a background in biological sciences, (bio)chemistry or a related discipline and should have a strong publication record in peer-reviewed journals. We are looking for talented, creative and enthusiastic candidates passionate for science and research.

  Our laboratory is a highly collaborative environment that values rigorous research. It is located at the main campus of EPFL, one of the two Swiss Federal Institutes of Technology, on the shores of Lake Geneva and at the foot of the Alps.

  Further details can be found on our website at ablasserlab@epfl.ch. Candidates are also encouraged to consult recent publications of the laboratory:

  Ablasser and Chen, Science 2019

  Haag et al., Nature 2018

  Glück et al., Nature Cell Biology 2017

  Gulen et al., Nature communications 2017

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