招聘簡介：

　　博士后免疫學(xué)研究員

　　·希望之城

　　·地點(diǎn)：加利福尼亞州杜阿爾特

　　·工作編號：7057371

　　·發(fā)布日期：2019年5月20日

　　·申請截止日期：開放至填寫

　　職位描述

　　貝克曼希望之城研究所正在加利福尼亞州杜阿爾特希望之城的Leo D.Wang博士的實(shí)驗(yàn)室里尋找一位才華橫溢的博士后研究員。

　　你喜歡免疫學(xué)，特別是T細(xì)胞受體信號？

　　你有興趣應(yīng)用這些知識來幫助開發(fā)新的癌癥療法嗎？

　　您對設(shè)計(jì)、領(lǐng)導(dǎo)和實(shí)施自己的項(xiàng)目感到興奮嗎？

　　我們正在招募熱情、積極的科學(xué)家，他們正在尋求一個(gè)快速、團(tuán)隊(duì)為基礎(chǔ)的學(xué)術(shù)研究環(huán)境。我們在免疫腫瘤學(xué)部門的實(shí)驗(yàn)室專注于血液和免疫細(xì)胞如何發(fā)展、功能和與其他細(xì)胞的相互作用，第二個(gè)重點(diǎn)是血液干細(xì)胞如何變得惡性。我們使用質(zhì)譜法來鑒定罕見的血干細(xì)胞和祖細(xì)胞群中的激活蛋白電路，包括治療性嵌合抗原受體（car）T細(xì)胞，并將這一知識與基本免疫原理結(jié)合，以改進(jìn)和設(shè)計(jì)新的治療兒童癌癥和血液疾病的方法。

　　英文原文：

　　Postdoctoral Fellow - Immunology

　　·         City of Hope

　　·         Location: Duarte, CA

　　·         Job Number: 7057371

　　·         Posting Date: May 20, 2019

　　·         Application Deadline: Open Until Filled

　　Job Description

　　The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow in the laboratory of Leo D. Wang, MD, PhD, at City of Hope, Duarte, CA.

　　Do you love immunology, particularly T cell receptor signaling?

　　Are you interested in applying that knowledge to help develop new cancer therapies?

　　Are you excited to design, lead, and implement your own projects?

　　We are recruiting enthusiastic, motivated scientists who are seeking a fast-paced, team-based academic research environment. Our lab in the Department of Immuno-oncology focuses on how blood and immune cells develop, function, and interact with other cells, with a second focus on how blood stem cells become malignant. We use mass spectrometry to identify activated protein circuits in rare blood stem and progenitor cell populations, including therapeutic chimeric antigen receptor (CAR) T cells, and combine that knowledge with fundamental immunological principles to improve and devise new therapies for pediatric cancers and blood disorders.

　　To learn more about our research, visit: www.leowanglab.org or

　　https://www.cityofhope.org/research/beckman-research-institute/research-departments-and-divisions/immuno-oncology/leo-wang-lab/leo-wang-lab-research.

　　Key Responsibilities

　　Design and lead multiple projects focused on understanding CAR signaling in brain-tumor-targeted CAR T cells, using canonical TCR signaling as a fundamental framework. Both in vitro and in vivo rodent work will be required.

　　Coordinate lab tasks and operations among multiple lab members, including ordering, inventory, and other essential lab functions.

　　Prepare laboratory reagents, chemicals, instruments, and maintain equipment.

　　Keep detailed and accurate logs of experiments from conception to analysis, as well as of lab inventory and rodent colonies.

　　Record data meticulously and analyze and synthesize results using industry standard application suites.

　　Help to prepare presentations and manuscripts for publication.

　　Initiate and maintain collaborations with other labs.

　　Travel to meetings to represent the lab and to present new data.

　　Basic education, experience and skills required for consideration:

　　Ph.D. in immunology or related field;

　　Expertise with flow cytometry, immunologic assays, cell culture, and molecular biology techniques is required;

　　Ability to work productively and meticulously;

　　Ability to develop cohesive team relationships;

　　Extensive prior experience in immunology or a closely related field;

　　Good oral and written communication skills;

　　Ability to structure tasks logically and effectively, organize, and set priorities;

　　Ability to respond effectively to constructive feedback;

　　Ability to analyze data statistically and to present it logically.

　　Preferred education experience and skills:

　　Experience with high-resolution imaging platforms and mass cytometry (CyTOF) or mass spectrometry is a plus;

　　Programming experience (R, Python) preferred.

　　Additional Information:

　　Ideal candidates will be highly motivated and have ambitions to further develop scientific and career skills. They will have a desire to be challenged and to learn new scientific strategies and techniques.

　　In addition to competitive compensation and benefits, candidates will have the opportunity to learn and to develop research publications and presentations, independent grant applications, and independent projects that they can take with them when they leave the lab.

　　Candidates will receive training in the safe handling of toxic chemicals, biohazards, animals, radiation, and other reagents.

　　City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

　　City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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