招聘簡介：

　　·莫菲特癌癥中心和研究所

　　·地點：佛羅里達(dá)州坦帕市

　　職位描述

　　莫菲特癌癥中心腫瘤生物學(xué)系的Premi實驗室正在尋找一位積極進(jìn)取的博士后研究員加入實驗室。我們感興趣的是研究梅蘭化學(xué)激發(fā)及其在黑素瘤起始，進(jìn)展和針對靶向治療的抗性中的作用。這包括但不限于皮膚色素的致癌性，它們在調(diào)節(jié)黑素瘤表觀遺傳學(xué)和腫瘤免疫學(xué)中的作用，以及黑素瘤進(jìn)展中的色素類型和量。

　　英文原文：

　　·         Moffitt Cancer Center and Research Institute

　　·         Location: Tampa, FL

　　Job Description

　　Premi lab at the department of Tumor Biology, Moffitt Cancer Center, is seeking a highly motivated postdoctoral fellow to join the lab. We are interested in investigating melnin chemiexcitation and its role in melanoma initiation, progression, and resistance against targeted therapies. This includes but not limited to carcinogenicity of skin pigments, their role in modulating melanoma epigenetics and tumor immunology, and pigment type and amount in melanoma progression.

　　Position Highlights:

　　• Work closely with the PI to discover unique, non-classical mechanisms of drug resistance in melanoma.

　　• Opportunities to present and discuss the data on institutional and national platforms, and develop collaborations to successfully pursue the scientific problems in hand.

　　The Ideal Candidate:

　　• Well trained in basic cell and molecular biology methods like DNA/RNA manipulation, immunodetection, (IHC/IF/western blotting), microscopy, and CRISPR and other knockdown/knockout methods.

　　• Experienced in culturing and maintaining mammalian cells that includes primary cells. Experince with melanocytes and other skin cells like primary fibrobalsts and keratinocytes is a plus.

　　• Experience with high-throughput proteomics and genomics is desirable.

　　Responsibilities:

　　• Lab management and maintainance in addition to performing experiments. This includes ordering , receiving, and properly storing reagents and other lab materials.

　　• Design and perform experiments with a limited supervision.

　　• Data analyses and reporting in seminars and meetings, writing manuscripts.

　　• Mentor graduate and undergraduate trainees in the lab.

　　Credentials and Qualifications:

　　• Candidate must have an M.D. or Ph.D. in Molecular Oncology or Molecular and Cellular Biology. Would like to have a candidate with publications in peer reviewed journals and at least 1 or 2 first author papers.

　　Interested applicants should send a single PDF file that includes a cover letter summarizing their research training and accomplishments, a personal statement of scientific interests and goals, current CV with recent publications, and contact information for three references to Dr. Sanjay Premi at sanjay.premi@moffitt.org.

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