招聘簡介：

　　·密歇根州立大學(xué)

　　·地點：密歇根州東蘭辛

　　職位描述

　　密歇根州立大學(xué)物理與天文學(xué)系的康斯托克實驗室正在尋找一名博士后研究員，以便在實驗室內(nèi)立即提供有關(guān)極端體外單分子生物物理學(xué)研究進展的研究進展。

　　康斯托克實驗室是一個新的實驗室，其中充滿了渴望突破基礎(chǔ)生物分子機器測量和觀察邊界的科學(xué)家。我們設(shè)計并構(gòu)建了新型光學(xué)捕獲和熒光儀器，可實現(xiàn)單分子生物測量的新模式。理想的候選人最近將獲得博士學(xué)位。在生物物理學(xué)，物理學(xué)，化學(xué)或生物化學(xué)或相關(guān)領(lǐng)域，已具備以下研究經(jīng)驗：1）使用和開發(fā)單分子實驗技術(shù)的經(jīng)驗，包括光學(xué)鑷子（最好是雙阱高分辨率版本），單分子熒光，F(xiàn)RET， 2）濕實驗室經(jīng)驗，包括新型核酸構(gòu)建體合成的詳細經(jīng)驗，包括基于DNA和RNA的構(gòu)建體，以及這些構(gòu)建體的標(biāo)記和純化，以及3）蛋白質(zhì)分子馬達的研究經(jīng)驗（例如，解旋酶，聚合酶等）和/或核酸或蛋白質(zhì)折疊。成功的候選人還將展示在高度協(xié)作的研究環(huán)境中工作的能力以及指導(dǎo)實驗室初級成員的潛力。

　　英文原文：

　　·         Michigan State University

　　·         Location: East Lansing, MI

　　Job Description

　　The Comstock Lab at Michigan State University in the Department of Physics and Astronomy is seeking a postdoctoral Research Associate for an immediately available position within the lab advancing research progress on topics of extreme in vitro single molecule biophysics.

　　The Comstock Lab is a new lab filled with scientists eager to push the boundaries of measurement and observation of fundamental biological molecular machines. We design and build novel optical trapping and fluorescence instrumentation that enable new modalities of single molecule biological measurement. The ideal candidate would have recently obtained a Ph.D. in Biophysics, Physics, Chemistry or Biochemistry or related fields and would already possess the following research experience: 1) experience using and developing single molecule experimental techniques including optical tweezers (preferably dual-trap high-resolution versions), single molecule fluorescence, FRET, etc. 2) wet lab experience including detailed experience with novel nucleic acid construct synthesis, including DNA- and RNA-based constructs, as well as labeling and purification of such constructs, and 3) research experience with protein molecular motors (e.g., helicases, polymerases etc.) and/or nucleic acid or protein folding. The successful candidate will also demonstrate the ability to work within a highly collaborative research environment and the potential to mentor junior members of the lab.

　　Contact Information:

　　Matt Comstock

　　mjcomsto@msu.edu

　　Physics and Astronomy

　　567 Wilson Road, Room 4238

　　East Lansing,Michigan

　　United States

　　Tel: 5178845645

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