招聘簡介：

　　美國佐治亞理工學(xué)院和埃默里大學(xué)醫(yī)學(xué)院生物醫(yī)學(xué)工程學(xué)院的Coulter生物混合系統(tǒng)實(shí)驗(yàn)室（https://www.biohybridlab.org/）分別在本科和研究生BME項(xiàng)目中排名第1和第3。該實(shí)驗(yàn)室是高度多學(xué)科的，主要研究心臟和骨骼肌工程。我們的目的是闡明：（1）生物系統(tǒng)如何協(xié)調(diào)其各個(gè)組成部分的層次結(jié)構(gòu)和功能，以產(chǎn)生緊急的物理行為，如形態(tài)發(fā)生、遷移和收縮；（2）破壞這種協(xié)調(diào)如何加劇疾病�；�于候選人的研究背景和興趣，該研究員將有機(jī)會(huì)從事潛在的項(xiàng)目：（1）通過使用攜帶患者特異性突變的誘導(dǎo)多能干細(xì)胞源性心肌細(xì)胞來模擬遺傳性肌肉疾��；（2）開發(fā)能夠進(jìn)行再灌注的交互式生物雜交機(jī)器人系統(tǒng)。養(yǎng)蜂組織和器官水平的協(xié)調(diào)功能，通過利用心臟和骨骼肌系統(tǒng)。該項(xiàng)目將融合分子生物學(xué)、肌肉機(jī)械/電子生物學(xué)、光學(xué)和機(jī)器人學(xué)，這些學(xué)科跨越了以前從未在單一系統(tǒng)中一起研究過的遠(yuǎn)程學(xué)科。

　　英文原文：

　　The biohybrid systems laboratory (https://www.biohybridlab.org/) of Sung-Jin Park, Ph.D. is housed in the Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University School of Medicine, ranked #1 and #3 in the USA among undergraduate and graduate BME programs, respectively. The laboratory is highly multidisciplinary with primary interests in cardiac and skeletal muscle engineering. We aim to elucidate (1) how biological systems coordinate the hierarchical structures and functions of their individual components in order to produce emergent physical behaviors such as morphogenesis, migration, and contraction and (2) how disrupting this coordination potentiates disease. Based on the candidate’s research background and interests, the fellow would have the opportunity to work on potential projects: (1) modeling inherited muscle diseases through the use of induced pluripotent stem cell-derived cardiomyocytes carrying patient-specific mutations and (2) developing interactive biohybrid robotic systems capable of recapitulating tissue- and organ-level coordinated functions by harnessing cardiac and skeletal muscle systems. The project will amalgamate molecular biology, muscle mechano/electro-biology, optics, and robotics, which span remote disciplines that previously have never been investigated together in a single system.

　　Applicants must hold a Ph.D. and/or MD degree (or the equivalent). Hands-on experience with the development of in vitro cell/tissue models or stem cell research is required. Additional experience in live cell imaging, cardiac and skeletal muscle tissue engineering, stem cell engineering, gene editing, molecular biology, single molecule fluorescence in situ hybridization (smFISH), optogenetics, microfabrication, tissue scaffold design and engineering, massive data and image processing, and computational modeling is desirable.

　　ality in education and employment.

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