招聘簡介：

　　博士后助理（眼科 - 藥物發(fā)現(xiàn)/開發(fā)）

　　·邁阿密大學

　　·地點：佛羅里達州邁阿密

　　·職位編號：7057458（參考編號：R100030943）

　　·發(fā)布日期：2019年5月28日

　　·申請截止日期：開放至填寫

　　職位描述

　　我們正在尋找兩位具有高度積極性的博士后研究員，他們在分子/細胞生物學和生物藥物發(fā)現(xiàn)和開發(fā)的動物研究方面擁有豐富的研究經(jīng)驗。這些職位是美國國立衛(wèi)生研究院資助的項目的一部分，該項目旨在開發(fā)邁阿密大學醫(yī)學院Bascom Palmer眼科研究所的新型藥物療法。 Bascom Palmer眼科研究所連續(xù)15年（2004年至2018年）被美國新聞和世界報道評為第一眼科醫(yī)院。

　　英文原文：

　　Postdoctoral Associate (Ophthalmology - Drug Discovery/Development)

　　·         University of Miami

　　·         Location: Miami, FL

　　·         Job Number: 7057458 (Ref #: R100030943)

　　·         Posting Date: May 28, 2019

　　·         Application Deadline: Open Until Filled

　　Job Description

　　We are searching for two highly-motivated postdoctoral associates with strong research experience in molecular/cellular biology and animal research for biological drug discovery and development. These positions are part of NIH-funded projects to develop novel drug therapies at Bascom Palmer Eye Institute, the University of Miami School of Medicine. Bascom Palmer Eye Institute has been ranked as the #1 eye hospital in the past 15 consecutive years (2004 -2018) by U.S. News and World Report.

　　Research will focus on developing next-generation targeted anti-angiogenic therapies for various vascular diseases. The laboratory recently developed the only technology of ligandomics with broad applicability to discover high-quality drug targets for novel therapies of different diseases, including but not limited to angiogenic diseases (PMID: 29326083). Using this powerful technology, we discovered highly promising drug targets and are developing targeted anti-angiogenic therapies for various ocular vascular diseases (PMID: 28330905). This project will investigate drug candidates in various stages. These include characterization of humanized antibodies to treat angiogenic diseases in animal models, analysis of novel drug targets in vitro and in vivo, and ligandomics screening to discover additional unknown drug targets. The research activities include ligandomics analysis, molecular and cellular studies, protein analyses, antibody characterizations, receptor identification and characterization, therapies to treat vascular leakage and pathological neovascularization in animal models, preclinical toxicology and pharmacokinetics studies. For more information, please visit our laboratory website and press release, or read publications.

　　Candidates must have a Ph.D. and/or MD, have productive scientific contributions through publication of high impact peer-reviewed papers, and show strong commitment to science. Applicants with advanced skills in molecular biology, cell biology, protein biochemistry, immunohistochemistry and animal research are highly desired. Experience in bioinformatics analysis is a plus. Excellent verbal and written communication skills are required. This position represents an excellent opportunity for career development in disease mechanism research and drug target discovery.

　　If interested, please send a CV, 1-2 page summary/Cover letter describing past accomplishments and 3 references, including contact information to Dr. Wei Li at w.li@med.miami.edu. Salary is based on NIH recommendation. Positions are available immediately.

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