招聘簡介：

　　博士后研究助理：寄生蟲的分子遺傳學(xué)和RNA生物學(xué)

　　·德克薩斯州A&M

　　·地點：德克薩斯州大學(xué)站

　　·工作編號：7057659（參考：教授）

　　·發(fā)布日期：2019年6月11日

　　·申請截止日期：2019年6月11日

　　工作描述

　　自2019年9月起，德克薩斯農(nóng)工大學(xué)生物化學(xué)和生物物理系的Cruz Reyes博士實驗室將提供博士后職位。

　　該項目將結(jié)合分子遺傳學(xué)和生物化學(xué)的方法，涉及蛋白質(zhì)組學(xué)、生物信息學(xué)和結(jié)構(gòu)生物學(xué)的組成部分。一條研究線是關(guān)于錐蟲寄生蟲RNA編輯過程的機制。錐蟲體內(nèi)的這個過程與RNAi、CRISPR/CAS9、mRNA剪接和其他由小的非編碼RNAs（NCRNAs）引導(dǎo)的系統(tǒng)有著有趣的相似之處。第二個研究項目是針對色氨酸體中的基本基因進行藥物開發(fā)，包括N-核糖基轉(zhuǎn)移酶、Cruzain和Tbcat B。申請人將參與我們與美國其他實驗室的合作研究。

　　英文原文：

　　Postdoctoral Research Associate: Molecular Genetics and RNA Biology in Parasites

　　·         Texas A&M

　　·         Location: College Station, TX

　　·         Job Number: 7057659 (Ref #: Professor)

　　·         Posting Date: Jun 11, 2019

　　·         Application Deadline: Jun 11, 2019

　　Job Description

　　A postdoctoral position is available starting September 2019 in Dr. Cruz-Reyes laboratory at Texas A&M University, Department of Biochemistry and Biophysics.

　　This project will combine approaches in molecular genetics and biochemistry, and involves components in proteomics, bioinformatics, and structural biology. One research line is on the mechanism of the RNA editing process in trypanosome parasites. This process in trypanosomes has interesting analogies with RNAi, CRISPR/Cas9, mRNA splicing and other systems directed by small non-coding RNAs (ncRNAs). A second research line involves projects in drug development against essential genes in trypanosomes including N-ribosyl transferases, cruzain, and TbCat B. The applicant will participate in both research lines in our collaborative studies with other labs in the USA.

　　Skills require direct experience in RNA biology or molecular genetics, and excellent verbal and written communication skills. Applicants should have a Ph.D. in biochemistry or molecular biology. Salary is commensurate with experience. The position is ideal and preferred for recent Ph.D. graduates. The applicants should send their CV, the names of three referees, and representative publications to cruzrey@tamu.edu

　　Texas A&M, one of the largest universities in the USA, is located in the heart of the Houston-Dallas-Austin triangle and within a two-hour drive of 26 million of the state’s 28 million residents, Texas A&M's main campus in College Station is home to more than 65,000 students from all over the world. College Station/Bryan is a Sun Belt metropolitan area with nearly 180,000 residents. It is consistently ranked among the best places to live in the country, yet retains a low cost of living with easy access to major Texas cities. Texas A&M University is an EO/AA/Vet/Disability Employer.

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