招聘簡(jiǎn)介：

　　癌癥生物學(xué)博士后研究員

　　·希望之城

　　·地點(diǎn)：加利福尼亞州杜阿爾特

　　·工作編號(hào)：7058178

　　·發(fā)布日期：2019年6月24日

　　·申請(qǐng)截止日期：開(kāi)放至填寫(xiě)

　　工作描述

　　霍普市貝克曼研究所癌癥生物學(xué)系有一個(gè)博士后研究員職位。我們正在尋找一個(gè)積極的博士后研究員，對(duì)研究衰老和癌癥感興趣。我們的實(shí)驗(yàn)室有興趣研究正常造血干細(xì)胞老化過(guò)程中的遺傳和表觀(guān)遺傳變化，以及導(dǎo)致基因組不穩(wěn)定、白血病發(fā)展和耐藥性的白血病干細(xì)胞。該實(shí)驗(yàn)室利用骨髓移植和基因敲除小鼠模型、干細(xì)胞生物學(xué)、分子和成像技術(shù)來(lái)研究造血/白血病干細(xì)胞以及基因不穩(wěn)定性的分子調(diào)控。杰出的候選人，尤其是少數(shù)族裔背景的候選人，也可能有資格獲得NIH T32的DNA損傷反應(yīng)和致癌信號(hào)項(xiàng)目博士后培訓(xùn)獎(jiǎng)學(xué)金。

　　理想的候選者應(yīng)該在分子生物學(xué)和細(xì)胞生物學(xué)方面有豐富的經(jīng)驗(yàn)。有血液學(xué)和嚙齒動(dòng)物模型經(jīng)驗(yàn)者優(yōu)先。候選人應(yīng)該自我激勵(lì)，有良好的工作效率記錄。

　　英文原文：

　　Postdoctoral Fellow - Cancer Biology

　　·         City of Hope

　　·         Location: Duarte, CA

　　·         Job Number: 7058178

　　·         Posting Date: Jun 24, 2019

　　·         Application Deadline: Open Until Filled

　　Job Description

　　A Postdoctoral Fellow position is available at the Department of Cancer Biology, Beckman Research Institute at City of Hope. We are looking for a highly motivated postdoctoral fellow interested in studying aging and cancer. Our lab is interested in studying genetic and epigenetic alterations during aging of normal hematopoietic stem cells and in leukemia stem cells that lead to genomic instability, leukemia development and drug resistance. The lab utilizes bone marrow transplantation and genetic knockout mouse models, stem cell biology, and molecular and imaging techniques to study hematopoietic/leukemic stem cells, and molecular regulation of genomic instability. The outstanding candidate, particularly with minority background, may also be eligible for NIH T32 postdoctoral training fellowship in the DNA-damage-response-and-oncogenic-signaling program.

　　The ideal candidate is expected to have extensive experience in molecular biology and cell biology. Experience with hematology and rodent models preferred. The candidate should be self-motivated, with a proven track record of productivity.

　　Basic education, experience and skills required for consideration:

　　A Ph.D. degree in life or biomedical sciences, or a related discipline is required;

　　Strong interest in aging and cancer biology;

　　Extensive experience with basic molecular and cell biology skills;

　　Experience with tissue collection, histology and immunohistochemistry;

　　Experience with cell culture, immunofluorescence, flow cytometry, and cell-sorting;

　　Strong work ethic;

　　Good problem solving skills and passion to follow relevant literature;

　　Ability to conduct independent research;

　　Excellent written and verbal communication skills; evidence of productivity reflected in first author publications in peer-reviewed journals.

　　Preferred education experience and skills:

　　PhD in Molecular Biology, Biochemistry, or Stem Cell Biology;

　　Experience in hematology and handling animal models;

　　Experience with epigenetic techniques.

　　Additional Information:

　　For more information about Dr. Chen's research, please click here.

　　City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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