招聘簡介：

　　在線粒體RNA的結(jié)構(gòu)生物化學(xué)博士后研究（獎學(xué)金）

　　卡羅林斯卡學(xué)院（AI）

　　斯德哥爾摩，瑞典

　　張貼約3天，7月20 agoexpires 2019

　　細(xì)胞與分子生物學(xué)部（CMB）是一部具有強(qiáng)烈的重點(diǎn)放在基礎(chǔ)科學(xué)。研究和教育conducts中巴在細(xì)胞生物學(xué)、分子生物學(xué)、發(fā)育生物學(xué)、干細(xì)胞生物學(xué)、腫瘤生物學(xué)和感染。

　　分

　　提供一個hällberg實(shí)驗(yàn)室是國際環(huán)境刺激的互動。我們是一部在細(xì)胞和分子生物學(xué)在斯德哥爾摩Karolinska研究所，瑞典，是世界領(lǐng)先的一́s醫(yī)科大學(xué)。實(shí)驗(yàn)室位于最近開了一biomedicum，藝術(shù)研究的建設(shè)。

　　我們是在尋求照顧者有興趣在學(xué)習(xí)和博士后研究員）的線粒體基因組的結(jié)構(gòu)細(xì)胞生物學(xué)分離和隔離。該項(xiàng)目是一個多學(xué)科協(xié)作的一部分，由Alice Wallenberg基金會和由克努特，在斯德哥爾摩大學(xué)Alexey amunts在組和組rorbach和喬安娜馬丁hällberg在卡羅林斯卡研究所。

　　關(guān)稅

　　該項(xiàng)目的目的是在ribosomal structurally和biochemically到成熟的過程。在《hällberg subproject協(xié)作，在很早的治療步驟（rRNA成熟的自然是共同轉(zhuǎn)錄與早期的處理步驟和他們的協(xié)調(diào)與結(jié)合蛋白（ribosomal和成熟的因素。涉及的主要技術(shù)是電子顯微鏡（低溫電磁），macromolecular crystallography和生物化學(xué)。在項(xiàng)目中，我們將使用這兩個國家和國際來源的低溫EM和同步輻射設(shè)施。此外，我們將研究使用冷凍EM，卡羅林斯卡學(xué)院的設(shè)施，一個新的3D EM krios 300 kV（K3 120c是該探測器）和安裝在一個低溫2019年秋（FIB / SEM是安裝的最后一年。

　　英文原文：

　　Postdoctoral studies in mitochondrial RNA structural biochemistry (scholarship)

　　Karolinska Institutet (KI)

　　Stockholm, Sweden

　　Posted about 3 days agoExpires on July 20, 2019

　　The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology.

　　Division

　　The Hällberg laboratory is offering a stimulating, interactive international environment. We are part of the Department of Cell and Molecular Biology at the Karolinska Institutet in Stockholm, Sweden, one of the world ́s leading medical universities. The lab is located in the recently opened Biomedicum, a state-of-the-art research building.

　　We are seeking a highly motivated and enthusiastic postdoctoral fellow interested in studying the structural cell biology of mitochondrial genome separation and segregation. The project is part of a multi-disciplinary collaboration – financed by the Knut and Alice Wallenberg Foundation – between the groups of Alexey Amunts at Stockholm University and the groups of Joanna Rorbach and Martin Hällberg at the Karolinska Institutet.

　　Duties

　　The project aims to structurally and biochemically characterize the ribosomal maturation process. The Hällberg subproject in the collaboration focuses on the very earliest mito-rRNA maturation steps that occur co-transcriptionally and involves the early processing steps and their coordination with binding of ribosomal proteins and maturation factors. Main techniques involved are electron microscopy (cryo-EM), macromolecular crystallography and biochemistry. In the project, we will utilize both national and international synchrotron sources and cryo-EM facilities. Furthermore for cryo-EM, we will utilise Karolinska Institutet’s new 3D-EM facility with a Krios 300 kV (K3 detector) and Talos 120C to be installed during the autumn of 2019 with a cryo-FIB/ SEM to be installed in the end of the year.

　　Entry requirements

　　We are looking for highly motivated, independent and driven candidates. The successful applicant will have a background either in structural biology or RNA/RNA-protein biochemistry willing to learn or develop skills in state-of-the-art techniques for studying the structural biochemistry of protein-RNA complexes. A documented ability to independently carry out experimental research projects is required, as are good communication skills in spoken and written English.

　　Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

　　A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

　　To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.

　　The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

　　Type of scholarship

　　The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

　　Application process

　　An application must contain the following documents in English or Swedish:

　　·         A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and a summary of skills and experience

　　·         A complete list of publications

　　·         A brief summary of current work (no more than one page)

　　The application is to be submitted on the Varbi recruitment system. Applications will be screened continuously and we might start the interview process before the last day of application.

　　Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.

　　Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.

　　Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

　　For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

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