亚洲无码午夜福利视频|日韩国产高清一区二区|欧美老熟妇XB水多毛多|狠狠色成人一区二区三区|在线观看国产精品露脸网站|在线观看一区二区三区视频|激情性无码视频在线观看动漫|99国产精品久久久久久久成人

您的位置:中國博士人才網(wǎng) > 博士后招收 > 海外博士后招收 > 法國國家科學(xué)研究中心 (CNRS) 基因組編輯/功能基因組學(xué)博士后職位

關(guān)注微信

法國國家科學(xué)研究中心 (CNRS) 基因組編輯/功能基因組學(xué)博士后職位

時間:2021-04-09來源:中國博士人才網(wǎng) 作者:佚名

Post-Doctoral Fellow in Regulation of Mammalian Genome Expression M/F

Description

This project aims aims at understanding the role of secondary DNA structures and their ligands in the regulation of genome expression. He/She will perform genome editing and functional genomics experiments to support its investigations in the laboratory.

The post-doctoral fellow will join the IGMM, which is a plurithematic CNRS research unit, offering an environment perfectly suited to the development of the proposed subject. This unit located on the CNRS campus/ Route de Mende in Montpellier is part of a rich scientific environment composed by the various institutes (IRIM, CRBM, CEFE, etc). In addition, several technical platforms (flow cytometry, imaging, metabolism, etc.) are available and complete the site. The team Transcription and Epigenomics is interested in basal and activated transcription mechanisms as well as the regulation of gene expression through regulatory elements (promoters and enhancers). We are looking for a motivated and dynamic postdoc with good knowledge in genome editing and functional genomics. The selected applicant will be offered a 1rst one year that could be renewed for one or two extra years. More information on : https: // www. igmm.cnrs.fr/en/team/transcription- epigenomique-dans-les-cel... Recent publications of the group : Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation. Maqbool MA, Pioger L, El Aabidine AZ, Karasu N, Molitor AM, Dao LTM, Charbonnier G, van Laethem F, Fenouil R, Koch F, Lacaud G, Gut I, Gut M, Amigorena S, Joffre O, Sexton T, Spicuglia S, Andrau JC. Cell Rep. 2020 Aug 18;32(7):108048. doi: 10.1016/j.celrep.2020.108048. The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre- insertion Sequence Biases and Post-insertion Selection. Sultana T, van Essen D, Siol O, Bailly-Bechet M, Philippe C, Zine El Aabidine A, Pioger L, Nigumann P, Saccani S, Andrau JC, Gilbert N, Cristofari G. Mol Cell. 2019 May 2;74(3):555-570.e7. doi: 10.1016/j.molcel.2019.02.036. Epub 2019 Apr 4 Tyrosine-1 of RNA Polymerase II CTD Controls Global Termination of Gene Transcription in Mammals. Shah N, Maqbool MA, Yahia Y, El Aabidine AZ, Esnault C, Forné I, Decker TM, Martin D, Schüller R, Krebs S, Blum H, Imhof A, Eick D, Andrau JC. Mol Cell. 2018 Jan 4;69(1):48-61.e6. doi: 10.1016/j.molcel.2017.12.009. Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation. Cauchy P, Maqbool MA, Zacarias-Cabeza J, Vanhille L, Koch F, Fenouil R, Gut M, Gut I, Santana MA, Griffon A, Imbert J, Moraes-Cabé C, Bories JC, Ferrier P, Spicuglia S, Andrau JC. Nucleic Acids Res. 2016 May 5;44(8):3567-85. doi: 10.1093/nar/gkv1475. Epub 2015 Dec 15. Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells. Soucie EL, Weng Z, Geirsdóttir L, Molawi K, Maurizio J, Fenouil R, Mossadegh- Keller N, Gimenez G, VanHille L, Beniazza M, Favret J, Berruyer C, Perrin P, Hacohen N, Andrau JC, Ferrier P, Dubreuil P, Sidow A, Sieweke MH. Science. 2016 Feb 12;351(6274):aad5510. doi: 10.1126/science.aad5510. Epub 2016 Jan 21. High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq.

Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation. Maqbool MA, Pioger L, El Aabidine AZ, Karasu N, Molitor AM, Dao LTM, Charbonnier G, van Laethem F, Fenouil R, Koch F, Lacaud G, Gut I, Gut M, Amigorena S, Joffre O, Sexton T, Spicuglia S, Andrau JC. Cell Rep. 2020 Aug 18;32(7):108048. doi: 10.1016/j.celrep.2020.108048. The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre- insertion Sequence Biases and Post-insertion Selection. Sultana T, van Essen D, Siol O, Bailly-Bechet M, Philippe C, Zine El Aabidine A, Pioger L, Nigumann P, Saccani S, Andrau JC, Gilbert N, Cristofari G. Mol Cell. 2019 May 2;74(3):555-570.e7. doi: 10.1016/j.molcel.2019.02.036. Epub 2019 Apr 4 Tyrosine-1 of RNA Polymerase II CTD Controls Global Termination of Gene Transcription in Mammals. Shah N, Maqbool MA, Yahia Y, El Aabidine AZ, Esnault C, Forné I, Decker TM, Martin D, Schüller R, Krebs S, Blum H, Imhof A, Eick D, Andrau JC. Mol Cell. 2018 Jan 4;69(1):48-61.e6. doi: 10.1016/j.molcel.2017.12.009. Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation. Cauchy P, Maqbool MA, Zacarias-Cabeza J, Vanhille L, Koch F, Fenouil R, Gut M, Gut I, Santana MA, Griffon A, Imbert J, Moraes-Cabé C, Bories JC, Ferrier P, Spicuglia S, Andrau JC. Nucleic Acids Res. 2016 May 5;44(8):3567-85. doi: 10.1093/nar/gkv1475. Epub 2015 Dec 15. Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells. Soucie EL, Weng Z, Geirsdóttir L, Molawi K, Maurizio J, Fenouil R, Mossadegh- Keller N, Gimenez G, VanHille L, Beniazza M, Favret J, Berruyer C, Perrin P, Hacohen N, Andrau JC, Ferrier P, Dubreuil P, Sidow A, Sieweke MH. Science. 2016 Feb 12;351(6274):aad5510. doi: 10.1126/science.aad5510. Epub 2016 Jan 21. High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq. Vanhille L, Griffon A, Maqbool MA, Zacarias-Cabeza J, Dao LT, Fernandez N, Ballester B, Andrau JC, Spicuglia S. Nat Commun. 2015 Apr 15;6:6905. doi: 10.1038/ncomms7905.

Eligibility criteria

The applicant should have a PhD in Genetics/Molecular Biology, preferably in the fields of transcription/chromatin and/or functional genomics. He/she will be familiar with CRISPR and high-throughput sequencing. Further knowledge in Bioinformatics analyses will be useful for the project but is not compulsory

Web site for additional job details

https: // emploi.cnrs.fr/Offres/CDD/UMR5535-SARADE-005/Default.aspx

為防止簡歷投遞丟失請抄送一份至:boshijob@126.com(郵件標(biāo)題格式:應(yīng)聘職位名稱+姓名+學(xué)歷+專業(yè)+中國博士人才網(wǎng))

中國-博士人才網(wǎng)發(fā)布

聲明提示:凡本網(wǎng)注明“來源:XXX”的文/圖等稿件,本網(wǎng)轉(zhuǎn)載出于傳遞更多信息及方便產(chǎn)業(yè)探討之目的,并不意味著本站贊同其觀點或證實其內(nèi)容的真實性,文章內(nèi)容僅供參考。

相關(guān)文章
城步| 静乐县| 阿拉善左旗| 宝应县| 扎兰屯市| 古交市| 青浦区| 文山县| 巴里| 芷江| 邵武市| 台北市| 古蔺县| 麦盖提县| 宁国市| 威远县| 富民县| 道孚县| 电白县| 泌阳县| 达拉特旗| 龙岩市| 宁晋县| 彭州市| 南平市| 怀柔区| 陆川县| 保德县| 永丰县| 太白县| 阿鲁科尔沁旗| 卢龙县| 壤塘县| 定西市| 昌黎县| 封开县| 当雄县| 兰西县| 青阳县| 凤冈县| 开远市|