美國(guó)貝勒醫(yī)學(xué)院藥物發(fā)現(xiàn)中心2025年招聘博士后職位（藥代動(dòng)力學(xué)）

貝勒醫(yī)學(xué)院（Baylor College of Medicine）是美國(guó)休斯敦的一所私立醫(yī)藥學(xué)校，被認(rèn)為是全美最杰出的醫(yī)學(xué)院之一，獲中國(guó)教育部認(rèn)證。學(xué)校在世界范圍內(nèi)的生物醫(yī)藥研究領(lǐng)域處于領(lǐng)先地位，學(xué)校最早建立于一九零零年，迄今為止已經(jīng)有一百多年的悠久歷史了。

貝勒醫(yī)學(xué)院為學(xué)生提供財(cái)政援助和獎(jiǎng)學(xué)金，幫助學(xué)生減輕就學(xué)期間的經(jīng)濟(jì)壓力，符合要求的學(xué)生都可以申請(qǐng)獎(jiǎng)學(xué)金和財(cái)政援助。學(xué)校致力于醫(yī)藥和研究生教育，并且因而獲得了超過(guò)一億美金的捐贈(zèng)，是美國(guó)六十三所獲得超過(guò)一億捐贈(zèng)的優(yōu)秀大學(xué)之一。

Postdoctoral Associate- Pharmacokinetics

Baylor College of Medicine

Summary

The Center for Drug Discovery ( https://www.bcm.edu/research/centers/drug-discovery ) is a strategic research center at Baylor College of Medicine in Houston, Texas. We are currently seeking highly motivated, well-organized and enthusiastic Postdoctoral Fellows contributing to our research in the fields of drug metabolism and toxicity, as well as the study of chemical properties that aid in crossing the blood-testis barrier (BTB). In our well-equipped laboratory, we utilize advanced instruments such as Thermos UHPLC-Q Exactive MS, Orbitrap Exploris™ 120, Thermo Quintus (triple quadruple), and Imaging mass spectrometry (IMS, Bruker timsTOF fleX MALDI-2) to conduct LC-MS-metabolomics, pharmacokinetics, and spatial metabolomics. Understanding the drug metabolism could predict the possible adverse events of drugs in clinic and also could reduce the risk of the drug candidates in drug development. Determining chemical features passing BTB will facilitate the drug development for therapeutic targets behind BTB. Baylor College of Medicine is located in the prestigious Texas Medical Center and offers a highly interactive environment and a strong infrastructure for research and career development. To obtain further details about the positions, feel free to email Dr. Feng Li ( fl3@bcm.edu ) directly.

Job Duties

Plans, designs and conducts experiments.

Characterizes the drug metabolites using High-resolution LC-MS and NMR.

Analyzes LC-MS data from mouse tissue and plasma to evaluate their abilities for passing through BTB.

Documents and interprets experimental results and report to principal investigators.

Conducts literature searches and summarizes information in an appropriate format for a particular study.

Helps to write and prepare manuscripts.

Performs other job related duties as assigned.

Minimum Qualifications

MD or Ph.D. in Basic Science, Health Science, or a related field.

No experience required.

Preferred Qualifications

Doctoral degree in Chemistry, Drug metabolism and pharmacokinetics, Pharmacology, and Toxicology, or a related Biomedical Science discipline.

Experience in medicinal chemistry and structural characterization using LC-MS and NMR.

Skilled in the identification of drug metabolites in vitro and in vivo.

Experience in working with animals, including animal treatment and tissue collection.

Have the ability to plan, design and conduct experiments, especially on drug metabolism, tissue distribution, and metabolites identification. Pharmacology and toxicology backgrounds is a plus.

Have the experience of preparing and writing the manuscript.

Have experience in LC-MS method development and sample preparation, and data analysis

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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