美國(guó)希望之城2025年博士后招聘（蛋白質(zhì)化學(xué)、晶體學(xué)和結(jié)構(gòu)生物學(xué)）

希望之城國(guó)家醫(yī)療中心(City of Hope NationalMedical Center)是一所頂尖的美國(guó)非盈利研究和治療中心，專注于癌癥、糖尿病和其他危及生命的疾病。

Postdoctoral Fellow - Protein Chemistry, Crystallography and Structure

City of Hope

Job Description

Join the forefront of groundbreaking research at the Beckman Research Institute ofCity of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

TheJohn Williamsresearch lab at City of Hope is seeking a Postdoctoral Fellow or a Staff Scientist to join an innovative team. Our research primarily focuses on structural and biophysical methods to identify sources of energy additivity and multivalency in macromolecular complexes and use these properties to develop new tools and novel therapeutics.

As a successful candidate, you will:

·Determine structure of modified antibodies with immune receptors

·Apply yeast display to stabilize and subsequent deimmunize proteases

·Create additional antibody variants to maximize the therapeutic activity in a clinical setting

Your qualifications should include:

·Ph.D. degree chemistry, biochemistry, structural biology, biophysics or a related discipline is required.

·Knowledge of protein engineering (cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance, Iosthermal Ttitration Calorimetry

Salary / Pay Rate Information:

Pay Rate: $34.00 - $37.55 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

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