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中國(guó)科學(xué)院上海巴斯德研究所蟲媒病毒研究組招收博后

時(shí)間:2017-03-07來源:未知 作者:91boshi
中國(guó)科學(xué)院上海巴斯德研究所是由中國(guó)科學(xué)院、上海市政府、法國(guó)巴斯德研究所三方共建的科學(xué)研究機(jī)構(gòu),面向國(guó)家傳染病預(yù)防與控制的重大需求和國(guó)際前沿,圍繞重大傳染性疾病的致病機(jī)制、免疫應(yīng)答規(guī)律及防治策略,開展基礎(chǔ)和應(yīng)用型研究,教育和培養(yǎng)創(chuàng)新型人才。 
  上海巴斯德所蟲媒病毒研究組課題組以新發(fā)突發(fā)病毒如流感病毒以及登革熱等蟲媒病毒為主要研究對(duì)象,這些病毒給公共衛(wèi)生和安全帶來了巨大的威脅,關(guān)于這些病毒在細(xì)胞和分子水平上的細(xì)胞嗜性和致病機(jī)理仍存在很多未知。我們通過體內(nèi)外實(shí)驗(yàn),揭示病毒致病因子、宿主促病毒因子或者限制性因子。 
  崗位描述: 
  現(xiàn)招聘博士后1名,2年固定合約,待遇從優(yōu),根據(jù)課題和項(xiàng)目情況決定是否延期。 
  1)開展新發(fā)突發(fā)蟲媒病毒性傳染病致病機(jī)制的課題研究。 
  2)建立蚊蟲病毒體內(nèi)外感染模型。 
  3)研究限制性宿主因子在病毒復(fù)制和疫情傳播中的作用。 
  應(yīng)聘條件: 
  1)需具備病毒學(xué)或相關(guān)專業(yè)博士學(xué)位。 
  2)具有扎實(shí)的病毒學(xué)研究背景,熟練掌握分子病毒學(xué)、分子生物學(xué)、細(xì)胞生物學(xué)實(shí)驗(yàn)技術(shù);具有CRISPR/Cas9基因編輯技術(shù)和蚊蟲實(shí)驗(yàn)經(jīng)驗(yàn)者優(yōu)先。 
  3)工作認(rèn)真踏實(shí),有高度的責(zé)任心、進(jìn)取心和主動(dòng)性;樂于學(xué)習(xí)新知識(shí)與新技術(shù)。 
  4)富有團(tuán)隊(duì)合作精神和良好的人際溝通能力,有較強(qiáng)的英文交流和讀寫能力,協(xié)作能力強(qiáng)。 
  5)需以第一作者發(fā)表過一篇或以上SCI收錄的論文。 
  應(yīng)聘方式:  
  請(qǐng)應(yīng)聘者將本人簡(jiǎn)歷(Curriculum vitae)、自薦信和推薦人聯(lián)系方式通過電子郵件發(fā)送至Prof. Dimitri Lavillette(dlaville@ips.ac.cn)和徐老師kxu@sibs.ac.cn,郵件標(biāo)題請(qǐng)注明應(yīng)聘崗位。對(duì)符合要求者將盡快安排面試。應(yīng)聘者資料恕不退還,招聘單位將予以嚴(yán)格保密。  
    本招聘啟示至招聘崗位招滿前一直有效。
  Post-doctoral position in Arbovirus group open at IPS, Shanghai, PR China 
  IPS(Institut Pasteur of Shanghai) is the first international institute under the Chinese Academy of Sciences (CAS). Founded in 2004 by CAS, the Institut Pasteur and the Shanghai Municipal Government, IPS is an independent, nonprofit life sciences institute that works closely with Chinese authorities to address public health problems. IPS creates synergies between the Institut Pasteur and CAS networks, leveraging all the assets of Shanghai, one of Asia’s leading business and technology hubs. IPS is engaged in broad research related to infectious diseases, including basic research, epidemiological investigation and vaccine research on HIV, viral hepatitis B and C, respiratory viruses, cancer-related viruses, zoonotic viruses (including mosquito-borne viruses), malaria, etc. Together with its academic and industry partners, IPS’s goal is to develop diagnostic, vaccine and therapeutic products to meet the challenges of emerging and re-emerging infectious diseases.  
  In group of Arbovirus, by studying both infections in mammals and insects, our global project wants to unveil the viral and/or host factors responsible for pathogenicity or resistance to infection. Using different model alphaviruses (Chikungunya…) and Flaviviruses (Dengue, Zika…), we want to explore: i) the host factors involved in entry, interspecies transmission and host susceptibility; and ii) the role of cell response in virus replication and the spreading of viruses in vivo. These understanding will help to develop new strategies to fight these public health and veterinary threats.  
  Job description: 
  This is a full-time, fixed-term position available for up to 2 years, with the possibility of extension subject to the availability of funding. The work mainly includes: 
  1.Pathogenesis study of emerging and re-emerging arboviruses.  
  2.Establish in vivo and in vitro mosquitoes infection models. 
  3.Study the role of host factor in virus replication and disease outbreak.  
  Candidates: 
  The successful candidate must be in possession of a PhD in Biological Sciences (mention Virology, mosquito genetics or cell biology). You must have a high level of expertise and skills in synthetic biology, molecular genetics and cloning. A demonstrable experience in working with genome editing technologies including CRISPR/Cas9 will be desirable. Demonstrable experience of working with mosquitoes would be desirable, as well as a good knowledge of insect biology, genetics and transgenesis. 
  You must be a highly motivated, innovative and creative individual with demonstrable ability to develop and apply new concepts, and a proactive approach to problem solving. The successful candidate must be able to organise and prioritise their own work with minimal supervision and to independently drive forward their research project. Good verbal and written communication skills in English, and proven ability to write clearly and succinctly for high profile publications are also essential.  
  Emerging successful track record of academic publications commensurate with experience. 
  Application:  
  Candidates are invited to contact Prof. Dimitri LAVILLETTE (dlaville@ips.ac.cn) and Dr. Ke Xu (kxu@sibs.ac.cn) for further details. Please send an application with the following: - Cover letter - Concise summary of previous research activities - Curriculum vitae including publication list and contact details for 2-3 referrals 

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