招聘簡介：

　　歐洲分子生物學實驗室-歐洲生物信息學研究所（EMBL-EBI）正在尋找一名博士后研究員加入格斯登研究小組，該小組在計算癌癥生物學領域工作。

　　癌癥是一種由我們細胞基因組中的突變終身積累所驅(qū)動的疾病。癌癥數(shù)據(jù)科學組開發(fā)并將統(tǒng)計方法應用于大型癌癥數(shù)據(jù)集，以深入了解癌癥的起源，并實施預測癌癥進展和結果的模型。為了實現(xiàn)這一目標，研究小組使用了數(shù)千到數(shù)百萬癌癥患者的基因組、轉(zhuǎn)錄組和成像數(shù)據(jù)集。

　　根據(jù)這些數(shù)據(jù)，老年人研究小組在檢測癌細胞的最初變化和預測癌癥發(fā)生率方面做出了一些貢獻。我們還開發(fā)了基因組分類方案，該方案表明，同一種癌癥通�？梢约毞譃槎鄠�基因不同的群體，并實施了基于每個患者的個體基因構成的詳細風險評估的個性化預后方案。 

　　英文原文：

　　The European Molecular Biology Laboratory – European Bioinformatics Institute (EMBL-EBI) is seeking a Postdoctoral Fellow to join the Gerstung research group, which works in the area of computational cancer biology.

　　Cancer is a disease driven by the life-long accumulation of mutations in our cell’s genomes. The cancer data science group develops and applies statistical methods to large cancer data sets to gain insight into the origins of cancer and to implement models to predict cancer progression and outcomes. To achieve this, the group works with genomic, transcriptomic and imaging data sets from thousands to millions of cancer patients.

　　The Gerstung group has made several contributions to detect the first changes in cancer cells and predict the rates of developing cancer, based on these data. We have also developed genomic classification schemes that showed that the same cancers can often be subdivided into multiple genetically distinct groups and implemented personalised prognostic schemes that yield a detailed risk assessment based on each patient’s individual genetic makeup.

　　Your role

　　As a Postdoctoral Fellow in the group you will contribute to our research portfolio, ranging from cancer evolution over imaging to large scale epidemiological data analysis projects. You will drive your own research project and collaborate closely with other members of the group as well as local and international collaboration partners.

　　You have

　　·         a doctoral degree or equivalent qualification in computational biology, statistics, physics or related field;

　　·         previous experience with advanced statistical and machine learning tools such as R, Python, or Matlab and have an interest to apply these skills to improve our understanding of cancer;

　　·         a strong publication record;

　　·         the ability to drive and contribute to research projects and independently develop new research ideas;

　　·         previous experience in coding and mastering large data volumes;

　　·         excellent communication skills to clearly present your research ideas to experts as well as lay audiences.

　　You might also have

　　·         experience with analysing genomic and other high-dimensional biomedical data sets

　　·         a background in molecular biology, or previous experience tackling biological questions;

　　·         used and developed tools for interactive reporting, such as Shiny.

　　Why join us

　　EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. The remuneration package comprises a competitive salary, a comprehensive pension scheme and health insurance, educational and other family related benefits where applicable, as well as financial support for relocation and installation. For more information about pay and benefits click here.

　　We have an informal culture, international working environment and excellent professional development opportunities but one of the really amazing things about us is the concentration of technical and scientific expertise – something you probably won’t find anywhere else.

　　If you’ve ever visited the campus you’ll have experienced first-hand our friendly, collegial and supportive atmosphere, set in the beautiful Cambridgeshire countryside. Our staff also enjoy excellent sports facilities including a gym, a free shuttle bus, an on-site nursery, cafés and restaurant and a library.

　　What else do I need to know

　　Applications are welcome from all nationalities and this will continue after Brexit. For more information please see our website. Visa information will be discussed in more depth with applicants selected for interview.

　　EMBL-EBI is committed to achieving gender balance and strongly encourages applications from women, who are currently under-represented at all levels. Appointment will be based on merit alone.

　　Informal enquiries can be directed to Dr Moritz Gerstung.

　　The initial contract is for a period of twelve months with the possibility of a fixed-term extension.

　　Applications will close at 23:00 British time on the date listed above.

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