英國(guó)弗朗西斯克里克研究所癌癥進(jìn)化和基因組不穩(wěn)定實(shí)驗(yàn)室2025年招聘博士后

弗朗西斯·克里克研究所（Francis Crick Institute）：2010年諾貝爾獎(jiǎng)得主、遺傳學(xué)家保羅·納斯提議將英國(guó)倫敦兩家最大的生物醫(yī)學(xué)研究中心（英國(guó)國(guó)家醫(yī)學(xué)研究所，英國(guó)癌癥研究中心）合并在一起，建立一個(gè)巨型實(shí)驗(yàn)室。

2015年11月實(shí)驗(yàn)室將竣工，2021年，這家耗費(fèi)6.5億英鎊（約63億人民幣）、占地9.3萬(wàn)平方米的研究所將全功率運(yùn)行，將有1600位科學(xué)家和工作人員在這里工作，它將成為歐洲最大的單一生物醫(yī)學(xué)實(shí)驗(yàn)室。

2024年12月18日，弗朗西斯·克里克研究所在《自然》雜志上宣稱(chēng)，他們首次在實(shí)驗(yàn)室中培育出脊索。

Postdoctoral Fellow – [C Swanton] Cancer Evolution and Genome Instability Laboratory

The Francis Crick Institute

Location: London

Salary: From £43,210 with benefits, subject to skills and experience.

Hours: Full Time

Contract Type: Fixed-Term/Contract

Placed On: 20th December 2024

Closes: 19th January 2025

Job Ref: R2013

The Cancer Evolution and Genome Instability lab are studying how cancers evolve in the body to spread and become resistant to therapy and finding new ways to treat them more effectively.

Lung cancer remains one of the most pressing public health concerns worldwide, demanding innovative research to address its complexities and challenges. To this end, our research presents two distinct yet intertwined project directions for a postdoc candidate. We are seeking applications from candidates with a broad range of competencies.

The first research direction investigates the role of non-mutagenic carcinogens in lung cancer initiation. Recent studies have brought to light the fact that most carcinogens do not solely rely on DNA mutations to drive cancer development.

The second research direction focuses on the impact of clonal hematopoiesis of indeterminate potential (CHIP)-the age-related acquisition of somatic mutations in hematopoietic stem cells—on lung cancer progression.

Key Responsibilities

The postholder will be responsible for:

Working within the multi-disciplinary team of clinicians, bioinformaticians and bench scientists in the Swanton lab, and collaborating with groups at the Francis Crick Institute and beyond, including academic and industry partners

Driving the project forward using relevant experimental and/or computational approaches

Keeping up to date with the relevant literature in the field of cancer biology

Attending and reporting research results at regular group meetings

Contributing to the dissemination of scientific results by means of writing papers for publication and presenting orally and in poster form at national and international meetings

Postdoctoral Fellows will lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

The closing date for applications is 19/01/2025

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